Whole slide pathology images from regional lymph node metastasis in colon adenocarcinoma produced at Region Gävleborg Clinical Pathology and Cytology department. Consists of fifty chronologically consecutive cases.

This dataset represents a second collection series in connection to the LNCO dataset using different collection and annotation parameters.

Keywords: Pathology, Annotated, Whole slide imaging, Lymph nodes, Cancer, Colon, Adenocarcinoma.

Sample images

Sample images with reduced image quality. Please click to preview.

Dataset information

Short name LNCO2
Cite as Gordan Maras, Martin Lindvall, and Claes Lundstrom (2020) Regional lymph node metastasis in colon adenocarcinoma, second collection series doi:10.23698/aida/lnco2
Field Pathology
Organ Colon
Age span
Title Regional lymph node metastasis in colon adenocarcinoma, second collection series
Author Gordan Maras
Martin Lindvall
Claes Lundstrom
Year 2020
DOI doi:10.23698/aida/lnco2
Status Completed
Version 1.2.0
Scans 1245
Annotations 2598
Size 651.76GB
Resolution 20x and 40x
Modality SM
Scanner Aperio Scanscope (20x)
Hamamatsu NanoZoomer (40x)
Stain Hematoxylin and eosin.
Phase
References
Access
constraints

Controlled access
Free for use in legal and ethical medical diagnostics research.
Please contact the copyright holder for terms of access.

AIDA BY license
Free for use within AIDA with attribution.

Copyright Copyright 2020 Linköping University, Claes Lundström
Download Please contact Gordan Maras, Joel Hedlund, or Claes Lundstrom to request access.

Annotation

Lymph nodes have been identified by an experienced pathologist and annotated using region-of-interest boxes (positive, negative, unassested). A few detailed polygons of tumor exist. See details below.

Annotation details

Labels

The following labels exists:

NOTE: roi_tumor annotations are not exhaustive, meaning, there might be more tumor areas in lgl_roi_tumor lymph nodes than annotated with roi_tumor annotations.

NOTE: Some roi_lgl_norm areas contain tumor cells that are from an accidental contamination of the glass during processing. This is normal during routine clinical work and a challenge that automated systems should deal with in an appropriate manner. This is a very easy task for human pathologists to discern.

Sampling procedure

Sampling procedure: Query for patients with confirmed adenocarcinomas that underwent colorectomy with subsequent lymphnode review as part of TNM-staging. Selected 50 chronologically consecutive cases from unique patients (no patient has more than one case).

Source: One medical clinic in Sweden. Same as for LNCO1.

Descriptive statistics

LNCO2
  patients: 50
  cases: 50
  images: 1245
     median dimensions(WxH px): 49920 x 38016
     median resolution (micrometer per pixel): 0.459896982
  annotations:
    number: 2598
    lymph node sections (roi) 2551
      which are negative 948
      which are positive 75
      which are unassessed 1517
    images with at least one approximate tumor annotation: 30

License

Controlled access

Free for use in legal and ethical medical diagnostics research. Please contact the copyright holder for terms of access.

AIDA BY license

License v1.2.1

Copyright 2020 Linköping University, Claes Lundström

Permission to use, copy, modify, and/or distribute this data within Analytic Imaging Diagnostics Arena (AIDA) for the purpose of medical imaging research with or without fee is hereby granted, provided that the above copyright notice and this permission notice appear in all copies, and that publications resulting from the use of this data cite the following works:

Gordan Maras, Martin Lindvall, and Claes Lundstrom (2020) Regional lymph node metastasis in colon adenocarcinoma, second collection series doi:10.23698/aida/lnco2.

THE DATA IS PROVIDED “AS IS” AND THE AUTHOR DISCLAIMS ALL WARRANTIES WITH REGARD TO THIS DATA INCLUDING ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS. IN NO EVENT SHALL THE AUTHOR BE LIABLE FOR ANY SPECIAL, DIRECT, INDIRECT, OR CONSEQUENTIAL DAMAGES OR ANY DAMAGES WHATSOEVER RESULTING FROM LOSS OF USE, DATA OR PROFITS, WHETHER IN AN ACTION OF CONTRACT, NEGLIGENCE OR OTHER TORTIOUS ACTION, ARISING OUT OF OR IN CONNECTION WITH THE USE OR CHARACTERISTICS OF THIS DATA.